If I am a business owner and make good money but have lots of expenses, and good assests? could they denied me the work permit?

Being a business owner is not a qualification for DACA. You should work with an attorney.

Would my wife have to leave the United States while we fix her papers?

We would not know that because we need to know many facts related to your guys' case to be able to answer this question.

Where should I live now because I left my husband?

You should probably call a women's help line. You also can enforce your I 864 contract with the husband for support.

Am I eligible to apply for "follow to join" option for my wife? (My currrent status: L1-A, I-140 approved, I-485 pending)

Your wife should apply for an L2 visa.

I need to apply for a Green Card but my spouse has been unemployed for 6 yrs due to sickness although has received no benefits.

You will have to find a joint sponsor it seems. Read instructions to form i 864 on www.uscis.gov.

Only if your conduct happened more than 5 years ago from the date of your application. Also, I recommend that you use an attorney, as technically...

What is the process of changing H1B to L2 (with EAD) visa for starting new venture?

You need to see a lawyer to discuss your questions. I suggest that you also start with researching qualifications for L1 status.

Can i

If are filing for i 485, you can ask for a work permit.

How effect

Only those who are outside and who do not have valid visas are affected. USCIS keeps processing internal applications.

Does getting housing assistance affect my husband adjusting his status?

He is not eligible for food stamps if you are sponsoring him based on i130. As a US citizen, you can receive public assistance.