Fayetteville, Arkansas was first inhabited by the Osage tribe of Native Americans, and later by the Cherokees. In 1836, Fayetteville was established with a seat in the first state legislature.
Fayetteville is home to several public figures including Senator J. William Fulbright and former President Bill Clinton.
A number of historically important properties from Civil War days reside in Fayetteville, including the Headquarters House. The Trail of Tears and Butterflied Overland Mail Route also pass through Fayetteville.