No. There are "covenant" marriages in some parts of the country, and those require pre-marital counselling and limit the grounds for divorce, but no U.S. state forces married couples to stay married if one of them wants out.
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No, that is not possible, as it would be unconstitutional to require someone to stay in a marriage they no longer wanted to be in. A prenuptial agreement can be entered into that could possibly provide for certain financial penalties for infidelity or other misconduct, but that is all.
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