You don't need to move offshore, you only need to start a company offshore and have them hire you to do the work.
This is an extremely regulated business. Do Not attempt to begin without seeking legal advice! Most lawyers on Avvo, including myself, offer a free phone consultation.
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Attorney Jaffe has given you the direction you need.
The answer given does not imply that an attorney-client relationship has been established and your best course of action is to have legal representation in this matter.
As my colleague mentioned it is a very regulated industry with strict regulations around the wire act; money laundering and such. Many individuals have tried and have ended up facing the federal prosecutions. check Netteller. Bodog etc...
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It is possible to do with some assets offshore. You do not need to by physically located outside the U.S., although obviously doing so makes it harder (not impossible, just more annoying) to come after you. This is, as noted, a highly regulated area. When I advise my gaming clients, I tell them that the gaming business involves risk. Gambling is built around risk, and as an operator, your risk is that you can potentially face serious criminal penalties (felony charges) and huge fines if you screw things up. You absolutely should take the time and spend the money to retain counsel to guide you through this process, and to represent your gaming business in the future. It is not an area that you want to skimp on.
I focus my practice on (video) gaming industry, casino gambling, and complex internet law issues, electronic free speech, entertainment law, copyright and trademark law, and computer fraud. I primarily represent game developers and founders of emergent internet technologies. The author is a Maryland attorney; however no answer given on Avvo is intended as legal advice or intended to create an attorney-client relationship.