You are always best putting it in writing and sending via certified mail RRR so that there is a record that you dispute the charges. Check your credit reports and alert them if it appears that you disputed the claim.
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Many doctors charge for missed appointments, unless the appointment is cancelled early enough for them to schedule another client.
If an appointment was made by the doctor, for you the patient, it likely has the same effect as if the patient has made the appointment, and under the cancellation policy, there may be a charge.
What is missing from your inquiry, is whether or not this is your doctor, or is it a strange new doctor that, out of the blue, someone made an appointment for you, which seems a rather odd situation.
You should probably try again, to talk to this doctor, to get an explanation, or an end to this billing.
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Are you sayng you never made the appointment? How can that be if they have your billing information? Doctors can charge for missed appointments. If you did not make the appointment, dispute the bill in writing and then forget about it until they sue you, whcih I doubt they will.
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It is best to write letters citing calls that you made. Thus, I would recommend calling the doctor's office, objecting to the bill, requesting the name of the person to whom you are speaking, and then document the content of your call in a letter. Be sure to put in the letter an objection to the bill, disputing the same. You also have the right to demand support for the claim, which I would do, orally and in writing.