Are there home remedies to get rid of acne scars?

Answered October 31, 2010 21:54. The best way to prevent acne scars is to get the offending acne under control and to avoid picking any/all acne lesions (which leads to further inflammation, collagen breakdown, and scarring). Once acne scars are evident, there is no topical cream or oral medication to reverse them. The best treatment options are offered through dermatologists who can perform laser treatments or filler injections to smooth the skin's surface.