My husband commited crime being under very heavy Rx medications. Can it be affirmative defence? Thank you for your answer.

In general, the voluntary ingestion of medications is not considered a defense, although under some circumstances it can be used to try to establish that the defendant lacked the mental intent to commit the crime. The specifics of this case, the medical treatment prescribed, the actual medications taken, the potential side-effects of the medication, the actual side-effects reported to the treating physician and other considerations would all need to be reviewed by your husband's lawyer to determine the viability of this type of argument, in conjunction with the crimes charged and a full review of the prosecution's case. Good luck.

DISCLAIMER Since I do not practice law in your State, this answer is provided solely for informational purposes, for you/your husband to use as a starting point when speaking directly with a lawyer in your State. This answer does not constitute legal advice, create an attorney-client relationship, or constitute attorney advertising. I urge you/your husband to immediately contact an experienced criminal defense lawyer admitted to practice law in your State before you make any decisions about this case.

If he chose to take the medication to begin with there will generally be no leniency as a result. Also, there is generally a very high standard for an intoxication defense