I am in F1 status now but will expire this May, at the same time, I received my asylum interview notice scheduled this May, at this point, can I apply OPT or not? what will happen if my asylum denied this June, do they still approve my OPT or not?
If I were you I would not rely on the internet in any such complex and vital to your future life matters like your legal status. Consider retaining a counsel as any mistakes may create a more complex legal situation for you.
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You should consult with your schools DSO.
Should you not have thought about all this before applying for asylum? If asylum is denied, you will find yourself in the same nonimmigrant status you are on the day the asylum is denied. If you are in no particular status, you will be referred to Immigration Court for removal proceedings during which the Government will seek to have you deported and you will get an opportunity for a de-novo hearing on the merits of your asylum claim before a much better, more impartial and qualified audience - an immigration judge.
The information contained in this answer is provided for informational purposes only, and should not be construed as legal advice on any subject matter,not should it be viewed as establishing an attorney client relationship of any kind.