Maybe you can do the EB-5 here if you meet the requirements under 245i law.

What if I apply for I-601 to waive the 3 or 10 yr bar? The reason I say this is because as I am the only child, and my parents would be over 50 by the time I file for adjustment under EB-5, given their health issues, I think I might be eligible to waive the bar by showing extreme hardship to them. Am I right?

no, you don't trigger any bars until you leave the country.